Bufo is a powerful psychedelic substance found in the Sonoran Desert Toad. It is known for its ability to produce intense and profound spiritual experiences, as well as its potential for therapeutic use. Some people have reported using 5-MeO-DMT as a tool for personal, spiritual growth and self-discovery, with the sacrament helping to bring about a greater understanding of the self, one's place in the world, and the interconnectedness of all things. Others have used it to help alleviate symptoms of mental health conditions, such as addiction, depression, anxiety and PTSD.